Surah An-Nahl 16:104

الَّذِينَ لاَ يُؤْمِنُونَ بِآيَـتِ اللَّهِ

(Verily, those who do not believe in Allah's Ayat,) Allah will not guide them, and theirs will be a painful punishment, meaning, the disbelievers and heretics who are known to the people as liars. The Messenger Muhammad ﷺ, on the other hand, was the most honest and righteous of people, the most perfect in knowledge, deeds, faith and conviction. He was known among his people for his truthfulness and no one among them had any doubts about that - to such an extent that they always addressed him as Al-Amin (the Trustworthy) Muhammad. Thus when Heraclius, the king of the Romans, asked Abu Sufyan about the attributes of the Messenger of Allah ﷺ, one of the things he said to him was, "Did you ever accuse him of lying before he made his claim" Abu Sufyan said, "No". Heraclius said, "He would refrain from lying about people and then go and fabricate lies about Allah"

Dalam ayat ini, Allah swt menegaskan bahwa tanpa iman kepada Allah swt dan Al-Qur'an sebagai wahyu-Nya, seseorang tidak akan mendapat petunjuk kepada kebenaran hakiki yang melepaskan dia dari azab. Orang-orang yang mengatakan bahwa Al-Qur'an itu buatan manusia atau dongeng-dongeng zaman kuno, tentu jauh dari hidayah Allah, dan tidak akan dapat menemukan jalan kebenaran.

Al-Qur'an yang seharusnya menjadi penuntun ditinggalkannya, sehingga mereka menjadi sesat. Oleh karena itu, mereka mudah terjerumus ke dalam kejahatan sehingga jiwanya menjadi kotor dan tertutup oleh noda-noda dosa. Mereka itu pasti sengsara dan tersiksa di dunia dan di akhirat.